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Jayne Building, Philadelphia, Pennsylvania, circa 1870

David Jayne (1798-1866) purchased a drug store in Philadelphia in 1836. His patent medicine business grew quickly, and he built this new building (designed by Thomas U. Walter) in 1850. The firm of Dr. D. Jayne and Son was one of the largest patent medicine firms in the United States, and this building was "the most conspicuous building of the time" in Philadelphia. It has since been demolished.

Wood engraving of Jayne Building

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